Description: Three Dimensional Human Organotypic Models for Biomedical Research by Fabio Bagnoli, Rino Rappuoli Estimated delivery 3-12 business days Format Hardcover Condition Brand New Description This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. Publisher Description This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab.Chapters Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers and Human Organotypic Models for Anti-infective Research of this book are available open access under a CC BY 4.0 license at link.springer.com. Author Biography Fabio Bagnoli is discovery project leader of research & development programs at GSK. Research conducted by Fabio led to the filing of several patents as well as publications on various human pathogens published in important peer-reviewed journals. He has served as editor of several publications and is the coordinator of an industrial-academic effort on human organotypic models. He holds a PhD in Molecular and Cellular Microbiology from the University of Padova and conducted post-doctoral studies at Stanford University under the guidance of Dr. Stanley Falkow and Dr. Manuel Amieva.Rino Rappuoli is Chief Scientist and Head External R&D at GSK Vaccines, based in Siena, Italy and Professor of Vaccinology at Imperial College, London. Prior positions: head of Vaccine R&D at Novartis, CSO of Chiron Corporation, head for R&D at Sclavo.He earned his PhD in Biological Sciences at the University of Siena, Italy, and was visiting scientist at Rockefeller University and Harvard Medical School.He is elected member of US National Academy of Sciences (NAS), the European Molecular Biology Organization (EMBO), and the Royal Society of London. Awards received: Gold Medal by the Italian President, Albert B Sabin Gold Medal, Canada Gairdner International Award, European Inventor Award for Lifetime Achievement, and Robert Koch Award. He was nominated third most influential person worldwide in the field of vaccines (Terrapin). He has published more than 700 works in peer-reviewed journals.He introduced novel scientific concepts: genetic detoxification; cellular microbiology; reverse vaccinology; pangenome. Developed licensed vaccines: acellular pertussis containing a non-toxic mutant of pertussis toxin; first conjugate vaccine against meningococcus C; MF59, the first vaccine adjuvant after aluminium salts; meningococcus B; CRM 197 used as carrier in many conjugate vaccines.Dr. Rappuoli is among theworld scientific leaders dedicated to the sustainability of global health. Details ISBN 303062451X ISBN-13 9783030624514 Title Three Dimensional Human Organotypic Models for Biomedical Research Author Fabio Bagnoli, Rino Rappuoli Format Hardcover Year 2021 Pages 265 Edition 1st Publisher Springer Nature Switzerland AG GE_Item_ID:137615342; About Us Grand Eagle Retail is the ideal place for all your shopping needs! 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Price: 178.46 USD
Location: Fairfield, Ohio
End Time: 2024-11-28T03:35:55.000Z
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ISBN-13: 9783030624514
Book Title: Three Dimensional Human Organotypic Models for Biomedical Researc
Number of Pages: VIII, 265 Pages
Publication Name: Three Dimensional Human Organotypic Models for Biomedical Research
Language: English
Publisher: Springer International Publishing A&G
Publication Year: 2021
Subject: Biotechnology, Immunology, Oncology
Item Weight: 20.5 Oz
Type: Textbook
Subject Area: Science, Medical
Author: Rino Rappuoli
Item Length: 9.3 in
Item Width: 6.1 in
Series: Current Topics in Microbiology and Immunology Ser.
Format: Hardcover
